# Cell culture good practices: mycoplasma contamination check
Mycoplasma is a genus of bacteria that belongs to the class Mollicutes. What sets mycoplasmas apart from many other bacteria is their lack of a cell wall. The absence of a rigid cell wall makes them resistant to certain antibiotics that target cell wall synthesis. Meaning that even if you have antibiotics in your cell culture media, you can have a mycoplasma contamination.
