- Nov 19, 2009
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Aaron authored
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- Oct 27, 2009
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Aaron authored
1. Updated the mergeBed documentation to describe the -names option which allows one to report the names of the features that were merged (separated by semicolons).
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- Oct 23, 2009
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Aaron authored
Changed windowBed to optionally define the left and right windows according to strandedness.
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- Oct 21, 2009
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Aaron authored
The memory usage is now less than 2.0 Gb.
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- Oct 20, 2009
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Aaron authored
Fixed an obvious bug in subtractBed causing incorrect behavior when two features in B overlapped with a feature in A.
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- Sep 18, 2009
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Aaron authored
=== Notable changes in this release === 1. coverageBed will optionally only count features in BED file A (e.g. sequencing reads) that overlap with the intervals/windows in BED file B. This has been requested several times recently and facilitates CHiP-Seq and RNA-Seq experiments. 2. intersectBed can now require a minimum __reciprocal__ overlap between intervals in BED A and BED B. For example, previously, if one used -f 0.90, it required that a feature in B overlap 90% of the feature in A for the "hit" to be reported. If one adds the -r (reciprocal) option, the hit must also cover 90% of the feature in B. This helps to exclude overlaps between say small features in A and large features in B: A ========== B ********************************************************** -f 0.50 (Reported), whereas -f 0.50 -r (Not reported) 3. The score field has been changed to be a string. While this deviates from the UCSC definition, it allows one to track much more meaningful information about a feature/interval. For example, score could now be: 7.31E-05 (a p-value) 0.334577 (mean enrichment) 2:2.2:40:2 (several values encoded in a string) 4. closestBed now, by default, reports __all__ intervals in B that overlap equally with an interval in A. Previously, it merely reported the first such feature that appeared in B. Here's a cartoon explaining the difference. **Prior behavior** A ============== B.1 ++++++++++++++ B.2 ++++++++++++++ B.3 +++++++++ ----------------------------------------- Result = B.1 ++++++++++++++ **Current behavior** A ============== B.1 ++++++++++++++ B.2 ++++++++++++++ B.3 +++++++++ ----------------------------------------- Result = B.1 ++++++++++++++ B.2 ++++++++++++++ Using the -t option, one can also choose to report either the first or the last entry in B in the event of a tie. 5. Several other minor changes to the algorithms have been made to increase speed a bit.
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- Sep 17, 2009
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Aaron authored
1. Fixed yet another bug in the parsing of "track" or "browser" lines. Sigh... 2. Change the "score" column (i.e. column 5) to b stored as a string. While this deviates from the UCSC convention, it allows significantly more information to be packed into the column.
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- Jul 22, 2009
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Aaron authored
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- Jun 15, 2009
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Aaron authored
1. Fixed a bug in peIntersectBed that prevented -a from being correctly handled when passed via stdin. 2. Added new functionality to coverageBed that calculates the density of coverage. 3. Fixed bug in genomeCoverageBed.
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- May 19, 2009
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Aaron authored
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- May 05, 2009
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Aaron Quinlan authored
1. Added strandedness to relevant programs (e.g. intersectBed, mergeBed, etc.) 2. Moved reportBed and reportBedRange to bedFile.cpp to clean up code 3. Sped up file parsing. Added lineFileUtilities.cpp 4. Added peIntersectBed
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