## What is mycoplasma and why check for mycoplasma contaminations?
Mycoplasma is a bacteria that can infect cell cultures and is one of the most common contaminants in cell culturing.
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There are two bacis testing methods for mycoplasma:
1. Direct culture in media
Direct culture is the most effective and sensitive method for detecting mycoplasma, but it is also the most difficult and time-consuming.
2. Indirect tests that measure specific characteristics of mycoplasma
There are a wide range of indirect test methods available for mycoplasma detection, including PCR-based kits, DNA fluorochome staining, autoradiography, ELISA, immunofluorescence, and specific biochemical assays. These tests are faster than direct culture and are often commercially available as kits.
